报告题目：Progress and opportunities in human population genome sequencing
报告人：Prof. Richard Durbin（The joint Head of Human Genetics at The Wellcome Trust Sanger Institute, UK）
时间：2012年8月28日（星期二）上午08：40 — 10：00
地点：三楼学术报告厅
【简介】Richard Durbin is joint Head of Human Genetics at The Wellcome Trust Sanger Institute. He has made multiple theoretical and algorithmic contributions to biological sequence analysis, and contributed to the human genome project and development of the Pfam, TreeFam and WormBase data resources. He is currently co-leading the 1000 Genomes Project to produce a deep catalogue of human genetic variation by large scale sequencing, and the UK10K collaboration to extend sequence based genetics to samples with clinically relevant phenotypes, and has renewed interests in genome assembly methods.
Richard has a BA in Mathematics, and a PhD in Biology from Cambridge University. Following postdoctoral research on neural networks at Stanford University, and 6 years at the MRC Laboratory of Molecular at the start of the C.elegans and human genome projects, he moved to the Sanger Institute where he was Head of Informatics from 1992-2006 and Deputy Director from 1997 to 2006. He was elected Fellow of the Royal Society in 2004, Member of EMBO in 2009 and Fellow of ISCB in 2011.
Richard's home page can be found at http://www.sanger.ac.uk/research/faculty/rdurbin
【报告内容】The dramatic decrease in DNA sequencing costs in the last few years has allowed direct full genome sequence studies of genetic diversity by sequencing multiple individuals. As well supporting evolutionary and population genetic studies, this also allows phenotype association studies to be extended to all types of genetic variation, not just common variation typed by genotyping chips. However, there are serious computational complexities in designing studies and analysing the data. Prof. Durbin will discuss some of the successes in adressing these issues, and some of the outstanding problems, illustrating with results from the 1000 Genomes Project and population sequencing projects from genetic isolates, where we can begin to build a near-complete picture of genetic variation.
欢迎全所科研人员和研究生参加！
遗传资源与进化国家重点实验室
2012.8.15 |
