代表性工作（*通讯作者）

1.   Bi R^#, Pan LN^#, Dai H^#, Sun CL^#, Li C^#, Lin HJ, Xie LP, Ma HX, Li L, Xie H, Guo K, Hou CH,  Yao YG*, Chen LN*, Zheng P*. Epigenetic characterization of adult rhesus monkey spermatogonial stem cells identifies key regulators of stem cell homeostasis. Nucleic Acids Research, 2024 Nov 13: gkae1013.

2.   Jiang F^#, Wang L^#, Dong Y, Nie W, Zhou H, Gao J, Zheng P*. DPPA5A suppresses the mutagenic TLS and MMEJ pathways by modulating the cryptic splicing of Rev1 and Polq in mouse embryonic stem cells. Proc Natl Acad Sci USA, 2023, 120(30):e2305187120.

3.   Gong D, Wang L, Zhou H, Gao J, Zhang W, Zheng P*. Long noncoding RNA Lnc530 localizes on R-loops and regulates R-loop formation and genomic stability in mouse embryonic stem cells. Stem Cell Reports, 2023, 18(4):952-968.

4.   Ma H^#, Ning Y^#, Wang L^#, Zhang W, Zheng P*. Lnc956 regulates mouse embryonic stem cell differentiation in response to DNA damage in a p53-independent pathway. Science Advances, 2023, 9(3):eade9742.

5.   Zhang W^#, Tang M^#, Wang L, Zhou H, Gao J, Chen Z, Zhao B*, Zheng P*. Lnc956-TRIM28-HSP90B1 complex on replication forks promotes CMG helicase retention to ensure stem cell genomic stability and embryogenesis. Science Advances, 2023, 9(4):eadf6277.

6.   Li C, Bi R, Wang L, Ma YH, Yao YG*, Zheng P*. Characterization of long-term ex vivo expansion of tree shrew spermatogonial stem cells. Zoological Research, 2023, 44(6):1080-1094.

7.   Zheng P. Current understanding of genomic stability maintenance in pluripotent stem cells. Acta biochimica et biophysica Sinica, 2022, 54(6), 858-863. (invited review)

8.   Qin DD^#, Zhou JK^#, He XC^#, Shen XY^#, Li C, Chen HZ, Yan LZ, Hu ZF, Li X, Lv LB, Yao YG*, Wang Z*, Huang XX*, Hu XT*, Zheng P*. Depletion of giant ANK2 in monkeys causes drastic brain volume loss. Cell Discovery, 2021, 7(1):113.

9.   Wang L^#, Li J^#, Zhou H, Zhang W, Gao J, Zheng P*. A novel lncRNA Discn fine-tunes replication protein A (RPA) availability to promote genomic stability. Nature Communications, 2021,12(1):5572.

10. Li JZ, Shang YF, Wang L, Zhao B, Sun CL, Li JL, Liu SL, Li C, Tang M, Meng FL*, Zheng P*. Genome integrity and neurogenesis of postnatal hippocampal neural stem/progenitor cells require a unique regulator Filia. Science Advances, 2020, 6(44):eaba0682.

11. Ma H^#, Zhai J^#, Wan H^#, Jiang X^#, Wang X, Wang L, Xiang Y, He X, Zhao ZA, Zhao B, Zheng P*, Li L*, Wang H*. In vitro culture of cynomolgus monkey embryos beyond early gastrulation. Science, 2019, 366(6467):eaax7890.

12. Zhang WD^#, Chen ZL^#, Zhang DF, Zhao B, Liu L, Xie ZY, Yao YG, Zheng P*. KHDC3L mutation causes recurrent pregnancy loss by inducing genomic instability of human early embryonic cells. PLoS Biology, 2019, 17(10):e3000468.

13. Luo X^#, He Y^#, Zhang C^#, He X^#, Yan L^#, Li M, Hu T, Hu Y, Jiang J, Meng X, Ji W, Zhao X, Zheng P*, Xu S*, Su B*. Trio deep-sequencing does not reveal unexpected off-target and on-target mutations in Cas9-edited rhesus monkeys. Nature Communications, 2019, 10(1):5525.

14. Liu D^#, Wang X^#, He D^#, Sun C^#, He X, Yan L, Li Y, Han JJ*, Zheng P*. Single-cell RNA-sequencing reveals the existence of naive and primed pluripotency in pre-implantation rhesus monkey embryos. Genome Research, 2018, 28 (10):1481–1493. (封面论文)

15. Zhao B^#, Zhang WD^#, Cun YX, Li JZ, Liu Y, Gao J, Zhu HW, Zhou H, Zhang RG, Zheng P*. Mouse embryonic stem cells have increased capacity for replication fork restart driven by the specific Filia-Floped protein complex. Cell Research, 2018, 28(1):69-89.

16. Wang XY^#, Liu DH^#, He DJ, Suo SB, Xia X, He XC, Han JJ*, Zheng P*. Transcriptome analyses of rhesus monkey pre-implantation embryos reveal a reduced capacity for DNA double strand break (DSB) repair in primate oocytes and early embryos. Genome Research, 2017, 27(4):567-579.

17. Li CH, Yan LZ, Ban WZ, Tu Q, Wu Y, Wang L, Bi R, Ji S, Ma YH, Nie WH, Lv LB, Yao YG*, Zhao XD*, Zheng P*. Long-term propagation of tree shrew spermatogonial stem cells in culture and successful generation of transgenic offspring. Cell Research, 2017, 27(2):241-252.

18. Guo K^#, Li CH^#, Wang XY, He DJ, Zheng P*. Germ stem cells are active in postnatal mouse ovary under physiological conditions. Molecular Human Reproduction, 2016, 22(5):316-328 (该工作受到杂志同期特邀评论, Mol Hum Reprod, 2016, 22:313-315).

19. Lu YQ, He XC, Zheng P*. Decrease in expression of maternal effect gene Mater is associated with maternal ageing in mice. Molecular Human Reproduction, 2016, 22(4):252-260.

20. Zhao B, Zhang WD, Duan YL, Lu YQ, Cun YX, Li CH, Guo K, Nie WH, Li L, Zhang R, Zheng P*. Filia is an ESC-specific regulator of DNA damage response and safeguards genomic stability. Cell Stem Cell, 2015, 16(6):684-698.

21. Zhao YQ^#, Ji S^#, Wang JK^#, Huang JF*, ZhengP*. mRNA-Seq and microRNA-Seq whole-transcriptome analysis of rhesus monkey ESC neural differentiation revealed the potential regulators of rosette neural stem cells. DNA Research, 2014, 21(5):541-54.

22. Zheng P*, Baibakov B, Wang XH, Dean J*. PtdIns(3,4,5)P3 is constitutively synthesized and required for spindle translocation during meiosis in mouse oocytes. Journal of Cell Science, 2013, 126(Pt 3):715-21.

23. Li L, Zheng P, Dean J*. Maternal control of early mouse development. Development, 2010, 137:859-870. (review)

24. Zheng P, Dean J*. Role of Filia, a maternal effect gene, in maintaining euploidy during cleavage stage mouse embryogenesis. Proc Natl Acad Sci USA, 2009, 106(18):7473-8.