吴东东，中国科学院昆明动物所研究员，灵长类进化遗传与发育课题组负责人。现任昆明动物所副所长，遗传进化与动物模型全国重点实验室主任。以灵长类动物为研究对象，多学科交叉研究探讨灵长类复杂性状的起源与进化遗传机制，推动非人灵长类在生物医药领域的应用。作为发起人，牵头发起了国际灵长类基因组计划。目前以通讯作者或共同通讯作者身份在Science、Cell、Nature Genetics、Nature Ecology & Evolution、Science Advances、PNAS 等期刊发表论文数十篇。部分成果入选2023年中国生命科学十大进展（第一完成人）。获得中国青年科技奖特别奖、中国科学院青年科学家奖、中国科学院五四青年奖章等奖项。

教育与工作经历

2002/09—2006/07  复旦大学，生命科学院， 学士学位

2006/09—2011/01  中国科学院昆明动物研究所，遗传学，博士学位

2011/01—2016/01  中国科学院昆明动物研究所，副研究员

2016.01—         中国科学院昆明动物研究所，研究员，博士生导师

2025.02—         中国科学院昆明动物研究所，副所长

代表性论文 (# 通讯作者)

1.  Wang S, Chen Z, Luo A, You X, Kitchener AC, Tu X, Thakur M, Umapathy G, Hu S, Zhang T, Zhang Y, Liu S, Ding Y, Liu F, Dai Q, Feng X, Li L, Pan Y, Zhang M, Roos C, Fan P#, Fu Q#, Wu DD#. Genome sequences of extant and extinct gibbons reveal their phylogeny, demographic history, and conservation status. Cell. 2025 S0092-8674(25)01181-X.

2.  Shao Y, Zhou L, Li F, Zhao L, Zhang BL, Shao F, Chen JW, Chen CY, Bi XP, Zhuang XL, Hu J, Sun Z, Li X, Wang D, Wang S, Wang YM, Chen W, Li G, Lu HM, Liu Y, Fan PF, Yu L, Li M, Liu ZJ, Tiley GP, Yoder AD, Roos C, Hayakawa T, Marques-Bonet T, Rogers J, Yao YG, Zhang YP, Wang W, Qi XG#, Zhang G#, Wu DD#. Phylogenomic analyses provide insights into primate evolution. Science. 2023 380(6648):913-924.(封面论文)

3.  Qi XG #, Wu J, Zhao L, Wang L, Guang X, Garber PA, Opie C, Yuan Y, Diao R, Li G, Wang K, Pan R, Ji W, Sun H, Huang Z, Xu C, Witarto AB, Jia R, Zhang C, Deng C, Qiu Q, Zhang G, Grueter C#, Wu DD#, Li B #. Adaptations to a cold climate promoted social evolution in Asian colobine primates. Science. 2023 380(6648):eabl8621

4.  Zhang BL, Chen Y, Zhang Y, Qiao Y, Wu Y, Zhang Y, Lu Y, You X, Li Y, Huang HD, Wang Q, Li Y, Wang Y, Xiao W, Duan H, Qiu MH, Chen NH, Yu X, Yang MM, Lv L, Cooper DN, Zheng P, Yao YG#, Liu N#, Wang JH#, Wu DD#. Forward and reverse genomic screens enhance the understanding of phenotypic variation in a large Chinese rhesus macaque cohort. Nature Communications. 2025 16(1):8703.

5.  Zhang BL, Chen W, Wang Z, Pang W, Luo MT, Wang S, Shao Y, He WQ, Deng Y, Zhou L, Chen J, Yang M, Wu Y, Wang L, Fernandez H, Molloy S, Meunier H, Wanert F, Kuderna L, Marques-Bonet T, Roos C, Qi X, Li M, Liu ZJ, Schierup MH, Cooper DN, Liu J, Zheng YT#, Zhang G#, Wu DD #. Comparative genomics reveal hybrid speciation of a macaque group. Science Advances. 2023 9(22):eadd3580.

6.  Bi X, Zhou L, Zhang J, Feng S, Hu M, Cooper DN, Lin J, Li J, Wu DD#, Zhang GJ#. Lineage-specific accelerated sequences underlying primate evolution. Science Advances. 2023 9(22):eadc9507

7.  Li ML, Wang S, Xu P, Tian HY, Bai M, Zhang YP, Shao Y, Xiong ZJ, Qi XG, Cooper DN, Zhang G, Zhu HH, Wu DD#. Functional genomics analysis reveals the evolutionary adaptation and demographic history of slow lorises. PNAS. 2022 119(40):e2123030119. (封面论文)

8.  AO, Zhang BL#, Meisel RP, Nneji LM, Shao Y, Morenikeji OB, Adeola AC, Ng'ang'a SI, Ogunjemite BG, Okeyoyin AO, Roos C, Wu DD#. Population Genomics Reveals Incipient Speciation, Introgression, and Adaptation in the African Mona Monkey (Cercopithecus mona). Molecular Biology and Evolution 2021 38(3):876-890.