(*通讯作者)
1. Benfu Zhong#, Dewei Jiang#, Yang Hong, Lifang Li, Li Qiu, Ronghui Yang, Xiaohan Jin, Yawen Song, Ceshi Chen*, Binghui Li*, Glucose-6-phosphate dehydrogenase neutralizes stresses by supporting reductive glutamine metabolism and AMPK activation,Signal Transduction and Targeted Therapy,2020, in press
2. Lina Zhao#, Ting Qiu#, Dewei Jiang#, Haibo Xu, Li Zou, Qin Yang, Ceshi Chen*, Baowei Jiao*, SGCE promotes breast cancer stem cells by stabilizing EGFR, Advanced Science, 2020, https://doi.org/10.1002/advs.201903700
3. Chao Dong#, Yin Chen#, Jing Ma#, Runxiang Yang#, Hongjian Li, Rong Liu, Dingyun You, Chunxiang Luo, Heng Li, Siyuan Yang, Kunbin Ke, Marie Chia-mi Lin*, Ceshi Chen*, Econazole nitrate reversed the resistance of breast cancer cells to Adriamycin through inhibiting the PI3K/AKT signaling pathway, American Journal of Cancer Research, 2020;10(1):263-274
4. Lingli He , Liang Yuan , Yang Sun , Pingyang Wang , Hailin Zhang , Xue Feng , Zuoyun Wang , Wenxiang Zhang , Chuanyu Yang , Yi Arial Zeng , Yun Zhao , Ceshi Chen*, Lei Zhang*, Glucocorticoid receptor signaling promotes breast cancer progression by activating TEAD4, Can Res, 2019, 79(17):4399-4411.
5. Yingying Wu, Qunying Qin , Fubing Li , Chuanyu Yang , Zhen Li , Zhongmei Zhou , Hailin Zhang , Yunxi Li , Xinye Wang , Rong Liu , Qian Tao , Wenlin Chen*, Ceshi Chen*, USP3 promotes breast cancer cell proliferation by deubiquitinating KLF5, J. Biol. Chem. 2019, 294(47),17837-47
6. Yanjie Kong*, Zehua Wang*, Maobo Huang, Zhongmei Zhou, Yi Li, Huilai Miao, Xing Wan, Jian Huang, Xiaoyun Mao#, Ceshi Chen#, CUL7 promotes cancer cell survival through promoting Caspase-8 ubiquitination, Int J Cancer, 2019
7. Chuan-Huizi Chen, Nong Yang, Yongchang Zhang, Jiancheng Ding, Wenjuan Zhang, Rong Liu, Wen Liu*, Ceshi Chen*, Inhibition of super enhancer downregulates the expression of KLF5 in basal-like breast cancers, Int J Biol. Sci., 2019; 15(8): 1733-1742.
8. Rong Liu*, Peiguo Shi, Zhongmei Zhou, Hailin Zhang, Ceshi Chen*, Krüpple-like factor 5 is Essential for Mammary Gland Development and Tumorigenesis, J Pathology, 2018, 246: 497-507
9. Huichun Liang#, Fei Ge#, Yuhui Xu#, Ji Xiao, Zhongmei Zhou, Rong Liu, Ceshi Chen, miR-153 inhibits the migration and the tube formation of endothelial cells by blocking the paracrine of angiopoietin 1 in breast cancer cells, Angiogenesis, (2018) 21:849–860.
10. Fubing Li#, Yang Li#, Huichun Liang#, Tao Xu#, Yanjie Kong, Chuanyu Yang, Maobo Huang, Zhongmei Zhou, Xiaomin Guo, Chunmiao Hu, Dongmei Zhou, Ceshi Chen*, Xiaopeng Qi*, HECTD3 mediates TRAF3 polyubiquitination and type I interferon induction during bacterial infection, J Clin Invest., 2018;128(9):4148-4162.
11. Huichun Liang, Ji Xiao, Zhongmei Zhou, Hailin Zhang, Zongcheng Li, Jian Sun, Fubing Li, Rong Liu*, and Ceshi Chen*, Hypoxia induces miR-153 through the IRE1α-XBP1 pathway to fine tune the HIF-1α/VEGFA axis in breast cancer angiogenesis, Oncogene, 2018, 37:1961-1975
12. Zekun Chen#, Qiuju Wu#, Ye Ding, Wenhui Zhou, Rong Liu, Haiying Chen, Jia Zhou*, Jing Feng*, Ceshi Chen*, YD277 Suppresses Triple-Negative Breast Cancer Partially Through Activating the Endoplasmic Reticulum Stress Pathway, Theranostics 2017; 7(8):2339-2349
13. Peiguo Shi, Wenjing Liu, Tala, Haixia Wang, Fubing Li, Hailin Zhang, Yingying Wu, Yanjie Kong, Zhongmei Zhou, Chunyan Wang, Wenlin Chen, Rong Liu, Ceshi Chen*, Metformin suppresses triple-negative breast cancer stem cells by targeting KLF5 for degradation, Cell Discovery, 2017, 3(17010)
14. Jing Wu, Ye Ding, Chuan-Hui zhi Chen, Zhongmei Zhou, Chunyong Ding, Haiying Chen, Jia Zhou*, Ceshi Chen*, A New Oridonin Analog Suppresses Triple-Negative Breast Cancer Cells and Tumor Growth via the Induction of Death Receptor 5. Cancer Letters, 2016, 380(2),393-402
15. Kong Y?, Li F?, Nian Y?, Zhou Z, Yang R*, Qiu MH*, Chen C*. KHF16 is a Leading Structure from Cimicifuga foetida that Suppresses Breast Cancer Partially by Inhibiting the NF-κB Signaling Pathway. Theranostics 2016; 6(6):875-886.
16. Rong Liu*, Peiguo Shi, Zhi Nie, Huichun Liang, Zhongmei Zhou, Wenlin Chen, Haijun Chen, Chao Dong, Runxiang Yang, Suling Liu, Ceshi Chen*,Mifepristone Suppresses Basal Triple-Negative Breast Cancer Stem Cells by Down-regulating KLF5 Expression,Theranostics 2016; 6(4): 533-544
17. Guang-Zhe Ge?, Hou-Jun Xia?, Bao-Li He, Hai-Lin Zhang, Wen-Jing Liu, Ming Shao, Chun-Yan Wang, Ji Xiao, Fei Ge, Fu-Bing Li, Yi Li, Ceshi Chen*, Generation and Characterization of a Breast Carcinoma Tree Shrew Model by PyMT Overexpression in Mammary Epithelial Cells, Int J Cancer, 2016,138(3),642-651
18. Junying Qin, Zhongmei Zhou, Wenlin Chen, Chunyan Wang, Hailin Zhang, Guangzhe Ge, Ming Shao, Dingyun You, Zhixiang Fan, Houjun Xia, Rong Liu, Ceshi Chen*, BAP1 promotes breast cancer cell proliferation and metastasis by deubiquitinating KLF5, Nature Communications, 2015, 6: 8471, doi:10.1038/ncomms9471
19. Lin Jia, Zhongmei Zhou, Huichun Liang, Jing Wu, Peiguo Shi, Fubing Li, Zehua Wang, Chunyan Wang, Wenlin Chen, Hailin Zhang, Yang Wang, Rong Liu, Jing Feng*, Ceshi Chen* KLF5 promotes breast cancer proliferation, migration and invasion in part by upregulating the transcription of TNFAIP2, Oncogene, 2015 Jul 20. doi: 10.1038/onc.2015.263.
20. Hou-Jun Xia?, Bao-Li He?, Chun-Yan Wang, Hai-Lin Zhang, Guang-Zhe Ge, Yuan-Xu Zhang, Long-Bao Lv, Jian-Lin Jiao, Ceshi Chen*, PTEN/PIK3CA genes are frequently mutated in spontaneous and MPA-accelerated DMBA induced mammary tumours of tree shrews, Eur J Cancer, 2014, 50(18):3230-3242
21. Yi Li?, Yanjie Kong?, Zhongmei Zhou, Hui Chen, Zehua Wang, Yi-Ching Hsieh, Dong Zhao, Xu Zhi, Jian Huang, Jing Zhang, Hongmin Li, Ceshi Chen* The HECTD3 E3 Ubiquitin Ligase Facilitates Cancer Cell Survival by Promoting K63-linked Polyubiquitination of Caspase-8, Cell Death and Disease, 2013, 4, e935
22. Xia H, Wang C, Chen W, Zhang H, Chaudhury L, Zhou Z, Liu R, Chen C*. Kruppel-Like Factor 5 Transcription Factor Promotes Microsomal Prostaglandin E2 Synthase 1 Gene Transcription in Breast Cancer. J Biol Chem. 2013 288(37):26731-40
23. Zehua Wang, Zhi Nie, Wenlin Chen, Zhongmei Zhou, Qinghua Kong, Arun Seth, Rong Liu*, Ceshi Chen*,RNF115/BCA2 E3 Ubiquitin Ligase Promotes Breast Cancer Cell Proliferation through Targeting p21 for Ubiquitin-mediated Degradation,Neoplasia, 2013 15(9):1028-35
24. Yi Li, Xi Chen, Zehua Wang, Dong Zhao, Hui Chen, Wenlin Chen, Zhongmei Zhou, Junran Zhang, Jing Zhang, Hongmin Li, Ceshi Chen*;The HECTD3 E3 Ubiquitin Ligase Suppresses Cisplatin-induced Apoptosis via Stabilizing MALT1,Neoplasia, 2013, 15(1):39-48
25. Xu Zhi, Dong Zhao, Zehua Wang, Zhongmei Zhou, Chunyan Wang, Wenlin Chen, Rong Liu*, Ceshi Chen*, E3 ubiquitin ligase RNF126 promotes cancer cell proliferation by targeting the tumor suppressor p21 for ubiquitin-mediated degradation, Cancer Res. 2013;73(1):385-94
26. Xu Zhi, Dong Zhao, Zhongmei Zhou, Rong Liu, Ceshi Chen*, YAP promotes breast cell proliferation and survival partially through stabilizing the KLF5 transcription factor, Am J Pathology, 2012, 180(6): 2452-61
27. Dong Zhao, Xu Zhi, Zhongmei Zhou, Ceshi Chen*, TAZ antagonizes theWWP1-mediated KLF5 degradation and promotes breast cell proliferation and tumorigenesis, Carcinogenesis, 2012, 33(1): 59-67
28. Rong Liu, Zhongmei Zhou, Dong Zhao,Ceshi Chen*, The induction of KLF5 transcription factor by progesterone contributes to progesterone-induced breast cancer cell proliferation and de-differentiation, Mol. Endocrinology, 2011, 25(7): 1137-1144 (Cover)
29. Rong Liu, Zhongmei Zhou, Jian Huang, Ceshi Chen*, PMEPA1 promotes androgen receptor negative prostate cell proliferation through suppressing the Smad3/4-c-Myc-p21Cip1 signaling pathway, Journal of Pathology, 2011, 223(5): 683-94
30. Dong Zhao, Hanqiu Zheng, Zhongmei Zhou, Ceshi Chen*, The Fbw7 tumor suppressor targets KLF5 for ubiquitin-mediated degradation and suppresses breast cell proliferation, Cancer Research, 2010, 70: 4728-38
31. Hanqiu Zheng, Zhongmei Zhou, Leena Chaudhury, Jin-Tang Dong, Ceshi Chen*, Krüpple-like factor 5 (KLF5) promotes breast cell proliferation partially through upregulating the transcription of fibroblast growth factor-binding protein 1 (FGF-BP) in breast cancer, Oncogene, 2009; 28: 3702-13.
32. Rong Liu, Hanqiu Zheng, Zhongmei Zhou, Jin-Tang Dong, Ceshi Chen*, KLF5 promotes breast cell survival partially through FGF-BP-pERK-mediated MKP-1 protein phosphorylation and stabilization, J Biol Chem., 2009 19; 284: 16791-8
33. Yi Li, Zhongmei Zhou, Maurizio Alimandi, Ceshi Chen*, WW domain containing E3 ubiquitin protein ligase 1 targets the full length ErbB4 for ubiquitin-mediated degradation in breast cancer, Oncogene, 2009 20; 28: 2948-58
34. Yi Li, Zhongmei Zhou, Ceshi Chen*, WW domain containing E3 ubiquitin protein ligase 1 targets p63 transcription factor for ubiquitin-mediated proteasomal degradation and regulates apoptosis, Cell Death and Differentiation, 2008, 15: 1941-51