| 著作名称: | Vitamins and Hormones: Hormones and Breast Cancer |
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| 主编: | Rong Liu, Jin-Tang Dong*, and Ceshi Chen* |
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| 出版社: | Academic Press of Elsevier |
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| 出版时间: | 2011 |
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| 著作简介: | Steroid hormones, including ovarian steroid hormones progesterone and estrogen and androgen, play vital roles in the development of normal mammary gland and breast cancer via their receptors. How these hormones regulate these physiological and pathological processes remains to be elucidated. Krüppel-like factor 5 (KLF5) is a transcription factor playing significant roles in breast carcinogenesis, whose expression has been shown to be regulated by hormones. In this review, the relationships among hormonal signaling, KLF5, and breast cancer are summarized and discussed. |
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