主要研究方向:濒危动物保护遗传学与基因组学
保护遗传学旨在研究影响物种濒危灭绝的遗传因素,促进濒危物种的遗传管理,最终保护物种的遗传多样性和演化潜力。基因组学技术的发展使保护遗传学研究逐渐进入到基因组水平,融合产生了保护基因组学这一新领域,一方面可以在基因组水平全面深入地揭示保护遗传学的传统问题,另一方面可以深入探讨物种适应性演化和种群局域适应的遗传学机制,进而从演化生物学角度理解濒危物种的适应机制,以进一步完善濒危物种的遗传管理。自2005年以来,胡义波研究员一直从事大熊猫和小熊猫等濒危哺乳动物的保护遗传学和适应性演化研究,围绕大、小熊猫趋同演化,大、小熊猫遗传多样性的时空格局和濒危历史等科学问题展开深入研究,相关论文以第一作者、共同第一作者及通讯作者身份发表在PNAS、Molecular Biology and Evolution、Ecology、Molecular Ecology、Ecology and Evolution等知名学术期刊上,并得到了国际同行和科学媒体的广泛关注和报道。今后研究重点是应用演化保护基因组学思想,解析濒危动物遗传变异的时空分布与演化格局及适应性性状演化的分子发育机制等科学问题。
Yu LJ, Nie YG, Yan L,Hu YB*, Wei FW. 2018. No evidence for MHC-based mate choice in wild giant pandas.Ecology and Evolution, doi: 10.1002/ece3.4419.
Ma S, Wu Q,Hu YB*, Wei FW. 2018. Patterns and effects of GC3 heterogeneity and parsimony informative sites on the phylogenetic tree of genes.Gene, 655, 56-60.
Hu YB, Wu Q, Ma S, Ma TX, Shan L, Wang X, Nie YG, Ning ZM, Yan L, Xiu YF, Wei FW*. 2017. Comparative genomics reveals convergent evolution between the bamboo-eating giant and red pandas.Proceedings of the National Academy of Sciences of the United States of America,114(5), 1081-1086.
Hu YB, Nie YG, Wei W, Ma TX, Van Horn R, Zheng XG, Swaisgood RR, Zhou ZX, Zhou WL, Yan L, Zhang ZJ, Wei FW*. 2017. Inbreeding and inbreeding avoidance in wild giant pandas.Molecular Ecology, 26(20), 5793-5806.
Wang D,Hu YB*, Ma TX, Nie YG, Xie Y, Wei FW. 2016. Noninvasive genetics provides insights into the population size and genetic diversity of an Amur tiger population in China.Integrative Zoology, 11(1), 16-24.
Chen ML#,Hu YB#, Liu JX, Wu Q, Zhang CL, Yu J, Xiao JF*, Wei FW*, Wu JY*. 2015. Improvement of genome assembly completeness and identification of novel full-length protein-coding genes by RNA-seq in the giant panda genome.Scientific Reports, 5, 18019.
Wei FW*,Hu YB, Yan L, Nie YG, Wu Q, Zhang ZJ. 2015. Giant pandas are not an evolutionary cul-de-sac: evidence from multidisciplinary research.Molecular Biology and Evolution, 32(1), 4-12.
Shan L#,Hu YB#, Zhu LF, Yan L, Wang CD, Li DS, Jin XL, Zhang CL, Wei FW*. 2014. Large-scale genetic survey provides insights into the captive management and reintroduction of giant pandas.Molecular Biology and Evolution, 31(10), 2663-2671.
Zhu LF#,Hu YB#, Qi DW, Wu H, Zhan XJ, Zhang ZJ, Bruford MW, Wang JL, Yang XY, Gu XD, Zhang L, Zhang BW, Zhang SN, Wei FW*. 2013. Genetic consequences of historical anthropogenic and ecological events on giant pandas.Ecology, 94(10), 2346-2357.
Wei FW*,Hu YB, Zhu LF, Bruford MW, Zhan XJ, Zhang L. 2012. Black and white and read all over: the past, present and future of giant panda genetics.Molecular Ecology,21(23), 5660-5674.
Hu YB, Guo Y, Qi DW, Zhan XJ, Wu H, Bruford MW, Wei FW*. 2011. Genetic structuring and recent demographic history of red pandas (Ailurus fulgens) inferred from microsatellite and mitochondrial DNA.Molecular Ecology,20, 2662-2675.
Hu YB, Zhan XJ, Qi DW, Wei FW*. 2010. Spatial genetic structure and dispersal of giant pandas on a mountain-range scale.Conservation Genetics, 11, 2145-2155.
Hu YB, Qi DW, Wang HJ, Wei FW*. 2010. Genetic evidence of recent population contraction in the southernmost population of giant pandas.Genetica, 138, 1297-1306.
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